Yale Center for Sleep Disturbance in Acute and Chronic Conditions

Mission and Goals

The Yale Center for Sleep Disturbance in Acute and Chronic Conditions (Grant number 1P20NR014126) is an exploratory research center, funded by the National Institute of Nursing Research, one of 27 institutes of the National Institutes of Health.

The Center is a collaborative effort between Yale School of Nursing (YSN) and Yale School of Medicine (YSM) and is led by Principal Investigators Nancy S. Redeker PhD, RN, FAHA, FAAN, Professor at YSN and Henry Klar Yaggi, MD, MPH Associate Professor in the Division of Pulmonary, Critical Care and Sleep Medicine at YSM and Director of the Yale Program in Sleep Medicine.

The mission of the Center is to promote the creation of knowledge that will lead to improvements in the assessment and bio-behavioral management of sleep disturbance across the trajectory of acute and chronic conditions and ultimately improvements in symptoms, function, quality of life, morbidity, and mortality.

The goals of the Center are to: 

  1. Expand the number and quality of research studies designed to improve understanding of: a) the bio-behavioral relationships between sleep disturbance and acute and chronic conditions; b) the contributions of sleep disturbance to morbidity, mortality, function and quality of life in the context of acute and chronic conditions; and c) assessment and bio-behavioral management of sleep disturbance across the trajectory of acute and chronic conditions in populations spanning the human lifespan and in various home and health care settings;
  2. Develop expertise among Center investigators in: a) ecologically valid sleep measurement methods that best capture the sleep attributes and sleep-related outcomes that are important in acute and chronic conditions and feasible in various populations and settings; b) statistical methods that address the multi-dimensional and temporal nature of sleep disturbance and chronic disease epidemiology and d) development and testing of interventions for management and self-management of sleep disturbance in acute and chronic conditions; 
  3. Build and sustain interdisciplinary partnerships within Yale and with external partners, including those in other NINR Centers, to increase research on sleep disturbance in acute and chronic conditions; and 
  4. Expand the strong research infrastructure at Yale to provide enhanced support for interdisciplinary sleep disturbance research.

Current Research

Gordon Buchanan, MD, PhD
Assistant Professor of Neurology, Yale University School of Medicine

Title: Serotonin neurons in arousal, epilepsy and SUDEP
Funding: NIH/NINDS

Title: Role of vigilance state and circadian phase in seizure-related death
Funding: Citizens United for Research in Epilepsy (Christopher Donnalty and Kyle Coggins Memorial Award for SUDEP research)

Hochang Benjamin Lee, MD
Associate Professor of Psychiatry, Yale University School of Medicine and Associate Clinical Professor of Nursing, Yale University School of Nursing; Director, Psychological Medicine Service

Title: Comparison of Structural and Functional Magnetic Resonance Imaging between Patients with Early-onset versus Late-onset Restless Leg Syndrome
FundingRLS Foundation

Peter Morgan, MD, PhD
Associate Professor, Yale University School of Medicine

Title: Modafinil, sleep architecture and cocaine relapse
FundingNIDA

Nancy Redeker, PhD, RN, FAHA, FAAN
Professor of Nursing, Yale University School of Nursing

TitleCognitive Behavioral Therapy for Insomnia in Stable Heart Failure
Funding: NIH/NINR

Title: Behavioral Treatment for Insomnia in Primary Care Settings
Funding: Yale School of Nursing

Title: Yale Center for Sleep Disturbance in Acute and Chronic Conditions
Funding: NIH/NINR