M.Tish Knobf, PhD, RN, FAAN

Tish Knobf

Professor of Nursing 
Chair, PhD Program 
Director Graduate Studies, PhD Program 

Yale School of Nursing - Room 20006

email: tish.knobf@yale.edu
phone: 203-737-2357
fax: 203-785-6455


Dr. Knobf is nationally and internationally recognized for her program of research with women diagnosed and treated for breast cancer, which has been grounded in her clinical practice. Her research spans descriptive quantitative and qualitative studies through intervention trials.  

Dr. Knobf holds a MSN from Yale School of Nursing and a PhD from the University of Pennsylvania. She has a strong commitment to mentoring students with pre and postdoctoral training programs, including the Komen Breast Cancer Interdisciplinary Disparities training grant and was honored by the Sigma Theta Tau Delta Mu Chapter mentorship award. Dr. Knobf’s contributions to nursing have been widely recognized including the Oncology Nursing Society, YSN Annie Goodrich Teaching award, American Cancer Society Professor of Oncology Nursing and the Connecticut Nurse’s Association Outstanding Contributions to Research award. Her expertise has interdisciplinary recognition at the institutional level and as a member  in national efforts in breast cancer, such as National Accreditation Program for Breast Centers.

Research Interests/Clinical Practice

Research Interests

Professor Knobf’s research has focused on the experience of women during and after breast cancer treatment, including persistent and late effects of therapy such as bone loss, weight gain, psychological distress and cardiovascular risks.  She has tested lifestyle and psycho-educational interventions to improve self-management to enhance health outcomes for breast cancer survivors and has addressed disparities and ethnic differences in the breast cancer experience.

Clinical Practice

Dr. Knobf’s clinical practice spans over the past three decades focusing on women with breast cancer.

Selected Publications/Presentations


Gormley, M., Knobf, M.T., Vorderstrasse, A., Aouizerat, B., Hammer, Fletcher, J., Melkus, G. (2021). Exploring the effects of genomic testing on fear of recurrence among breast cancer survivors. Psycho-oncol, doi.org/10.1002/pon.5679
Sanft, T., Harrigan, M., Cartmel, B., Ferrucci, L., McGowan, C., Zupa, M., Nguyen, T., Ligibel, J., Neuhauser M., Hershman, D., Basen-Enquist, K., Jones, B., Knobf, M.T., Chagpar, A., Silber, A., Irwin, M.  (2021) Effect of a healthy diet and exercise on chemotherapy completion rate in women with breast cancer. The Lifestyle Exercise and Nutrition Early after Diagnosis (LEANer) study: study protocol for a randomized clinical trial. Contemporary Clinical Trials Vol 109, https://doi.org.10.1016/j.cct.2021.106508
Knobf, M.T., Major-Campos, M., Maura M., Muse, S.R, Silber, A. (2021)  Bridging the care continuum: A pilot program for underserved women with breast cancer. J Oncol Navigation   (CEU feature), 12(8), 247-251.
Hwang, Y., Knobf, M.T. (2022). A narrative review of sleep in young women with breast cancer. Support Care Cancer, 30, 6419-6428.
Knobf, M.T., Hwang, Y., Sumpio, C., Barbarotto, l, Slusser, K. (2022). “Doing it Together: Struggling, Adapting and Holding Each Other up”. A qualitative study of oncology nurses during the first year of the pandemic. Oncol Nurs Forum, 49(6), 491-499.
Hwang, Y., Conley, S., Jeon, S., Redeker, N.S., Sanft, T., Knobf, M.T. (2022). Factors Associated with Sleep in Young Women with Breast Cancer. RINAH, 45(6), 680-692.
Liang, M., Chen, P., Molassiotis, A., Jeon, S., Tang, Y., Hu, G., Zhu, Y., Su, Z., Yu, Y., Knobf, M.T., Ye, Z.  (2023). Measurement of variance of 10-item resilience scale specific to cancer in Americans and Chinese: a propensity score-based multidimensional item response theory analysis. Asian-Pacific Journal Oncol Nurs, doi.org/10.1016/jpjon.2022.100171
Hwang, Y., Knobf, M.T., Sanft, T., Redeker, N. (2024). A qualitative study of sleep in young breast cancer survivors. “No Longer Able to Sleep through the Night”. J Cancer Survivorship18, 828-835. 
Rao, V. Linsky, S, Knobf MT (2024). Perspectives of patients with relapsed and refractory acute myeloid leukemia and high risk myelodysplastic syndrome on patient-clinicaal communication about prognosis and the future. Palliative Med Reports doi: 10.1089/pmr.2023.0064
Liang, M., Chen, P., Tang, Y., Tang X., Molassiotis, A., Knobf, M.T.,…. Ye, Z. (2024). Brain connectomics improve prediction of high-risk depression profiles in the first year following breast cancer diagnosis. Depression Anxiety doi: 10.1155/2024/3103115